- Seven interstates are within close proximity: I-81 (1 mile), I-26 (2 miles), I-381 (6 miles), I-77 (6 miles), I-75 (24 miles), I-64 (28 miles), and I-40 (36 miles).
- Four-lane highways in the region (U.S. 19, 23, 58, 460 and 421) increase connectivity to major interstates and markets.
- Freight rail service is provided by CSX Transportation and Norfolk Southern, offering a wide range of reliable and efficient shipping options.
- The Virginia TradePort, located at the New River Valley Airport, is 67 miles north, and The Port of Virginia, offering the deepest harbor on the U.S. East Coast, is 387 miles east.
- Six regional airports provide general aviation service, and Tri-Cities Regional Airport (TRI) provides commercial air service with connections to Atlanta, Charlotte, and Orlando/Tampa.